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Signaling models for dopamine-dependent temporal contiguity in striatal synaptic plasticity

Animals remember temporal links between their actions and subsequent rewards. We previously discovered a synaptic mechanism underlying such reward learning in D1 receptor (D1R)-expressing spiny projection neurons (D1 SPN) of the striatum. Dopamine (DA) bursts promote dendritic spine enlargement in a...

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Detalles Bibliográficos
Autores principales: Urakubo, Hidetoshi, Yagishita, Sho, Kasai, Haruo, Ishii, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402527/
https://www.ncbi.nlm.nih.gov/pubmed/32701987
http://dx.doi.org/10.1371/journal.pcbi.1008078