An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

The COVID-19 pandemic, caused by infection with the SARS-CoV-2 coronavirus, is having a deleterious impact on health services and the global economy, highlighting the urgent need for an effective vaccine. Such a vaccine would need to rapidly confer protection after one or two doses and would need to...

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Detalles Bibliográficos
Autores principales: Erasmus, Jesse H., Khandhar, Amit P., O’Connor, Megan A., Walls, Alexandra C., Hemann, Emily A., Murapa, Patience, Archer, Jacob, Leventhal, Shanna, Fuller, James T., Lewis, Thomas B., Draves, Kevin E., Randall, Samantha, Guerriero, Kathryn A., Duthie, Malcolm S., Carter, Darrick, Reed, Steven G., Hawman, David W., Feldmann, Heinz, Gale, Michael, Veesler, David, Berglund, Peter, Heydenburg Fuller, Deborah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402629/
https://www.ncbi.nlm.nih.gov/pubmed/32690628
http://dx.doi.org/10.1126/scitranslmed.abc9396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402629/
https://www.ncbi.nlm.nih.gov/pubmed/32690628
http://dx.doi.org/10.1126/scitranslmed.abc9396

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