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Microglial calcium signaling is attuned to neuronal activity in awake mice

Microglial calcium signaling underlies a number of key physiological and pathological processes in situ, but has not been studied in vivo in awake mice. Using multiple GCaMP6 variants targeted to microglia, we assessed how microglial calcium signaling responds to alterations in neuronal activity acr...

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Detalles Bibliográficos
Autores principales: Umpierre, Anthony D, Bystrom, Lauren L, Ying, Yanlu, Liu, Yong U, Worrell, Gregory, Wu, Long-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402678/
https://www.ncbi.nlm.nih.gov/pubmed/32716294
http://dx.doi.org/10.7554/eLife.56502