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Effects of α-tocopherol on hemolysis and oxidative stress markers on red blood cells in β-thalassemia major

BACKGROUND: The accumulation of unpaired α-globin chains in patients with β-thalassemia major may clinically create ineffective erythropoiesis, hemolysis, and chronic anemia. Multiple blood transfusions and iron overload cause cellular oxidative damage. However, α-tocopherol, an antioxidant, is a po...

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Detalles Bibliográficos
Autores principales: Sovira, Nora, Lubis, Munar, Wahidiyat, Pustika Amalia, Suyatna, Franciscus D., Gatot, Djajadiman, Bardosono, Saptawati, Sadikin, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Pediatric Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402984/
https://www.ncbi.nlm.nih.gov/pubmed/32668823
http://dx.doi.org/10.3345/cep.2019.00542