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Selection of chromatographic methods for the purification of cell culture-derived Orf virus for its application as a vaccine or viral vector
In recent years, the Orf virus has become a promising tool for protective recombinant vaccines and oncolytic therapy. However, suitable methods for an Orf virus production, including up- and downstream, are very limited. The presented study focuses on downstream processing, describing the evaluation...
Autores principales: | Lothert, Keven, Pagallies, Felix, Feger, Thomas, Amann, Ralf, Wolff, Michael W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403136/ https://www.ncbi.nlm.nih.gov/pubmed/32763261 http://dx.doi.org/10.1016/j.jbiotec.2020.07.023 |
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