Mammalian histones facilitate antimicrobial synergy by disrupting the bacterial proton gradient and chromosome organization

First proposed as antimicrobial agents, histones were later recognized for their role in condensing chromosomes. Histone antimicrobial activity has been reported in innate immune responses. However, how histones kill bacteria has remained elusive. The co-localization of histones with antimicrobial p...

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Detalles Bibliográficos
Autores principales: Doolin, Tory, Amir, Henry M., Duong, Leora, Rosenzweig, Rachel, Urban, Lauren A., Bosch, Marta, Pol, Albert, Gross, Steven P., Siryaporn, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403156/
https://www.ncbi.nlm.nih.gov/pubmed/32753666
http://dx.doi.org/10.1038/s41467-020-17699-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403156/
https://www.ncbi.nlm.nih.gov/pubmed/32753666
http://dx.doi.org/10.1038/s41467-020-17699-z

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