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Mammalian histones facilitate antimicrobial synergy by disrupting the bacterial proton gradient and chromosome organization
First proposed as antimicrobial agents, histones were later recognized for their role in condensing chromosomes. Histone antimicrobial activity has been reported in innate immune responses. However, how histones kill bacteria has remained elusive. The co-localization of histones with antimicrobial p...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403156/ https://www.ncbi.nlm.nih.gov/pubmed/32753666 http://dx.doi.org/10.1038/s41467-020-17699-z |