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Low Shear Stress Upregulates CX3CR1 Expression by Inducing VCAM-1 via the NF-κB Pathway in Vascular Endothelial Cells

Atherosclerosis is a significant cause of mortality and morbidity. Studies suggest that the chemokine receptor CX3CR1 plays a critical role in atherogenesis. Shear stress is an important mechanical force that affects blood vessel function. In this study, we investigated the effect of shear stress on...

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Detalles Bibliográficos
Autores principales: Zhao, Yiwei, Ren, Peile, Li, Qiufang, Umar, Shafiu Adam, Yang, Tan, Dong, Yahui, Yu, Fengxu, Nie, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403166/
https://www.ncbi.nlm.nih.gov/pubmed/32686027
http://dx.doi.org/10.1007/s12013-020-00931-4