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Multiplexed Optical Sensors in Arrayed Islands of Cells for multimodal recordings of cellular physiology

Cells typically respond to chemical or physical perturbations via complex signaling cascades which can simultaneously affect multiple physiological parameters, such as membrane voltage, calcium, pH, and redox potential. Protein-based fluorescent sensors can report many of these parameters, but spect...

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Detalles Bibliográficos
Autores principales: Werley, Christopher A., Boccardo, Stefano, Rigamonti, Alessandra, Hansson, Emil M., Cohen, Adam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403318/
https://www.ncbi.nlm.nih.gov/pubmed/32753572
http://dx.doi.org/10.1038/s41467-020-17607-5