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The Human LL-37(17-29) antimicrobial peptide reveals a functional supramolecular structure
Here, we demonstrate the self-assembly of the antimicrobial human LL-37 active core (residues 17–29) into a protein fibril of densely packed helices. The surface of the fibril encompasses alternating hydrophobic and positively charged zigzagged belts, which likely underlie interactions with and subs...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403366/ https://www.ncbi.nlm.nih.gov/pubmed/32753597 http://dx.doi.org/10.1038/s41467-020-17736-x |