Systematized reporter assays reveal ZIC protein regulatory abilities are Subclass-specific and dependent upon transcription factor binding site context

The ZIC proteins are a family of transcription regulators with a well-defined zinc finger DNA-binding domain and there is evidence that they elicit functional DNA binding at a ZIC DNA binding site. Little is known, however, regarding domains within ZIC proteins that confer trans-activation or -repre...

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Detalles Bibliográficos
Autores principales: Ahmed, Jehangir N., Diamand, Koula E. M., Bellchambers, Helen M., Arkell, Ruth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403390/
https://www.ncbi.nlm.nih.gov/pubmed/32753700
http://dx.doi.org/10.1038/s41598-020-69917-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403390/
https://www.ncbi.nlm.nih.gov/pubmed/32753700
http://dx.doi.org/10.1038/s41598-020-69917-9

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