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Systematized reporter assays reveal ZIC protein regulatory abilities are Subclass-specific and dependent upon transcription factor binding site context
The ZIC proteins are a family of transcription regulators with a well-defined zinc finger DNA-binding domain and there is evidence that they elicit functional DNA binding at a ZIC DNA binding site. Little is known, however, regarding domains within ZIC proteins that confer trans-activation or -repre...
Autores principales: | Ahmed, Jehangir N., Diamand, Koula E. M., Bellchambers, Helen M., Arkell, Ruth M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403390/ https://www.ncbi.nlm.nih.gov/pubmed/32753700 http://dx.doi.org/10.1038/s41598-020-69917-9 |
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