Opa1 Overexpression Protects from Early-Onset Mpv17(−/−)-Related Mouse Kidney Disease

Moderate overexpression of Opa1, the master regulator of mitochondrial cristae morphology, significantly improved mitochondrial damage induced by drugs, surgical denervation, or oxidative phosphorylation (OXPHOS) defects due to specific impairment of a single mitochondrial respiratory chain complex....

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Detalles Bibliográficos
Autores principales: Luna-Sanchez, Marta, Benincá, Cristiane, Cerutti, Raffaele, Brea-Calvo, Gloria, Yeates, Anna, Scorrano, Luca, Zeviani, Massimo, Viscomi, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403474/
https://www.ncbi.nlm.nih.gov/pubmed/32562616
http://dx.doi.org/10.1016/j.ymthe.2020.06.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403474/
https://www.ncbi.nlm.nih.gov/pubmed/32562616
http://dx.doi.org/10.1016/j.ymthe.2020.06.010

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