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Opa1 Overexpression Protects from Early-Onset Mpv17(−/−)-Related Mouse Kidney Disease
Moderate overexpression of Opa1, the master regulator of mitochondrial cristae morphology, significantly improved mitochondrial damage induced by drugs, surgical denervation, or oxidative phosphorylation (OXPHOS) defects due to specific impairment of a single mitochondrial respiratory chain complex....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403474/ https://www.ncbi.nlm.nih.gov/pubmed/32562616 http://dx.doi.org/10.1016/j.ymthe.2020.06.010 |