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Trimetazidine Inhibits Renal Tubular Epithelial Cells to Mesenchymal Transition in Diabetic Rats via Upregulation of Sirt1

Trimetazidine (TMZ), as a metabolic regulator, is effective in treatment of coronary atherosclerotic heart disease with rare side effects in the clinic for long years. Interestingly, studies have shown that TMZ protects against several acute kidney injuries (AKI). However, the effect of TMZ on chron...

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Detalles Bibliográficos
Autores principales: Yang, Yong, Wang, Yong, He, Zuowen, Liu, Yunchang, Chen, Chen, Wang, Yan, Wang, Dao Wen, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403491/
https://www.ncbi.nlm.nih.gov/pubmed/32848753
http://dx.doi.org/10.3389/fphar.2020.01136