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Quantitative analysis of heparan sulfate using isotopically labeled calibrants
Heparan sulfate is a sulfated polysaccharide that displays essential physiological functions. Here, we report a LC-MS/MS-based method for quantitatively determining the individual disaccharide composition and total amount of heparan sulfate. Using eight (13)C-labeled disaccharide calibrants and one...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403576/ https://www.ncbi.nlm.nih.gov/pubmed/32753592 http://dx.doi.org/10.1038/s42003-020-01150-6 |