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Quantitative analysis of heparan sulfate using isotopically labeled calibrants

Heparan sulfate is a sulfated polysaccharide that displays essential physiological functions. Here, we report a LC-MS/MS-based method for quantitatively determining the individual disaccharide composition and total amount of heparan sulfate. Using eight (13)C-labeled disaccharide calibrants and one...

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Detalles Bibliográficos
Autores principales:	Wang, Zhangjie, Arnold, Katelyn, Xu, Yongmei, Pagadala, Vijayakanth, Su, Guowei, Myatt, Hannah, Linhardt, Robert J., Liu, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403576/ https://www.ncbi.nlm.nih.gov/pubmed/32753592 http://dx.doi.org/10.1038/s42003-020-01150-6

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