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Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma

Activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL) is an aggressive subtype of lymphoma usually associated with inferior outcomes. ABC-DLBCL exhibits plasmablastic features and is characterized by aberrancies in the molecular networks controlled by IRF4. The signaling pathways that are...

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Detalles Bibliográficos
Autores principales: Ricker, Edd, Verma, Akanksha, Marullo, Rossella, Gupta, Sanjay, Ye, Chao, Pannellini, Tania, Manni, Michela, Tam, Wayne, Inghirami, Giorgio, Elemento, Olivier, Cerchietti, Leandro, Pernis, Alessandra B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403583/
https://www.ncbi.nlm.nih.gov/pubmed/32753663
http://dx.doi.org/10.1038/s41598-020-69884-1