Cargando…

IL-17F induces inflammation, dysfunction and cell death in mouse islets

Type 17 immune responses, typified by the production of the cytokines IL-17A and IL-17F, have been implicated in the development of type 1 diabetes in animal models and human patients, however the underlying pathogenic mechanisms have not been clearly elucidated. While previous studies show that IL-...

Descripción completa

Detalles Bibliográficos
Autores principales: Catterall, Tara, Fynch, Stacey, Kay, Thomas W. H., Thomas, Helen E., Sutherland, Andrew P. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403586/
https://www.ncbi.nlm.nih.gov/pubmed/32753746
http://dx.doi.org/10.1038/s41598-020-69805-2