Direct and Efficient C(sp(3))–H Functionalization of N-Acyl/Sulfonyl Tetrahydroisoquinolines (THIQs) With Electron-Rich Nucleophiles via 2,3-Dichloro-5,6-Dicyano-1,4-Benzoquinone (DDQ) Oxidation

A highly efficient metal-free oxidative direct C(sp(3))–H functionalization of N-acyl/sulfonyl 1,2,3,4-tetrahydroisoquinolines (THIQs) with a wide range of electron-rich nucleophiles was accomplished under mild conditions through oxidation with DDQ and subsequent trapping of the resulting reactive a...

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Detalles Bibliográficos
Autores principales: Yu, Heesun, Kim, Hyoungsu, Baek, Seung-Hoon, Lee, Dongjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403605/
https://www.ncbi.nlm.nih.gov/pubmed/32850649
http://dx.doi.org/10.3389/fchem.2020.00629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403605/
https://www.ncbi.nlm.nih.gov/pubmed/32850649
http://dx.doi.org/10.3389/fchem.2020.00629

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