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Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug-Resistant Cells

BACKGROUND: LCL161, a SMAC’S small molecule mimetic, can bind to a variety of IAPs and activate Caspases. We found that on its own, LCL161induces apoptosis of drug-resistant breast cancer cells by binding to a variety of IAPs and activating Caspases. However, when LCL161 is used in combination with...

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Detalles Bibliográficos
Autores principales: Jin, Gongshen, Wang, Kangwei, Liu, Yonghong, Liu, Xianhu, Zhang, Xiaojing, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403652/
https://www.ncbi.nlm.nih.gov/pubmed/32053082
http://dx.doi.org/10.2174/1871520620666200213102849