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Proteomic Level Changes on Treatment in MCF-7/DDP Breast Cancer Drug-Resistant Cells
BACKGROUND: LCL161, a SMAC’S small molecule mimetic, can bind to a variety of IAPs and activate Caspases. We found that on its own, LCL161induces apoptosis of drug-resistant breast cancer cells by binding to a variety of IAPs and activating Caspases. However, when LCL161 is used in combination with...
Autores principales: | Jin, Gongshen, Wang, Kangwei, Liu, Yonghong, Liu, Xianhu, Zhang, Xiaojing, Zhang, Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403652/ https://www.ncbi.nlm.nih.gov/pubmed/32053082 http://dx.doi.org/10.2174/1871520620666200213102849 |
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