Extensive flavivirus E trimer breathing accompanies stem zippering of the post‐fusion hairpin

Flaviviruses enter cells by fusion with endosomal membranes through a rearrangement of the envelope protein E, a class II membrane fusion protein, into fusogenic trimers. The rod‐like E subunits bend into “hairpins” to bring the fusion loops next to the C‐terminal transmembrane (TM) anchors, with th...

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Detalles Bibliográficos
Autores principales: Medits, Iris, Vaney, Marie‐Christine, Rouvinski, Alexander, Rey, Martial, Chamot‐Rooke, Julia, Rey, Felix A, Heinz, Franz X, Stiasny, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403712/
https://www.ncbi.nlm.nih.gov/pubmed/32484292
http://dx.doi.org/10.15252/embr.202050069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403712/
https://www.ncbi.nlm.nih.gov/pubmed/32484292
http://dx.doi.org/10.15252/embr.202050069

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