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Extensive flavivirus E trimer breathing accompanies stem zippering of the post‐fusion hairpin
Flaviviruses enter cells by fusion with endosomal membranes through a rearrangement of the envelope protein E, a class II membrane fusion protein, into fusogenic trimers. The rod‐like E subunits bend into “hairpins” to bring the fusion loops next to the C‐terminal transmembrane (TM) anchors, with th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403712/ https://www.ncbi.nlm.nih.gov/pubmed/32484292 http://dx.doi.org/10.15252/embr.202050069 |