Oxidative stress induces monocyte‐to‐myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma

BACKGROUND: Cancer‐associated fibroblasts (CAFs) are among the most prominent cells during the desmoplastic reaction in pancreatic ductal adenocarcinoma (PDAC). However, CAFs are heterogeneous and the precise origins are not fully elucidated. This study aimed to explore whether monocytes can transdi...

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Detalles Bibliográficos
Autores principales: Huang, Xin, He, Chaobin, Hua, Xin, Kan, Anna, Mao, Yize, Sun, Shuxin, Duan, Fangting, Wang, Jun, Huang, Peng, Li, Shengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403727/
https://www.ncbi.nlm.nih.gov/pubmed/32508052
http://dx.doi.org/10.1002/ctm2.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403727/
https://www.ncbi.nlm.nih.gov/pubmed/32508052
http://dx.doi.org/10.1002/ctm2.41

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