Access to PCNA by Srs2 and Elg1 Controls the Choice between Alternative Repair Pathways in Saccharomyces cerevisiae

During DNA replication, stalling can occur when the replicative DNA polymerases encounter lesions or hard-to replicate regions. Under these circumstances, the processivity factor PCNA gets ubiquitylated at lysine 164, inducing the DNA damage tolerance (DDT) mechanisms that can bypass lesions encount...

Descripción completa

Detalles Bibliográficos
Autores principales: Arbel, Matan, Bronstein, Alex, Sau, Soumitra, Liefshitz, Batia, Kupiec, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403780/
https://www.ncbi.nlm.nih.gov/pubmed/32371600
http://dx.doi.org/10.1128/mBio.00705-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403780/
https://www.ncbi.nlm.nih.gov/pubmed/32371600
http://dx.doi.org/10.1128/mBio.00705-20

Ejemplares similares