Chronic myelomonocytic leukaemia stem cell transcriptomes anticipate disease morphology and outcome

BACKGROUND: Chronic myelomonocytic leukaemia (CMML) is a clinically heterogeneous stem cell malignancy with overlapping features of myelodysplasia and myeloproliferation. Over 90% of patients carry mutations in epigenetic and/or splicing genes, typically detectable in the Lin(−)CD34(+)CD38(−) immuno...

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Detalles Bibliográficos
Autores principales: Wiseman, Daniel H, Baker, Syed M, Dongre, Arundhati V, Gurashi, Kristian, Storer, Joanna A, Somervaille, Tim CP, Batta, Kiran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403890/
https://www.ncbi.nlm.nih.gov/pubmed/32763828
http://dx.doi.org/10.1016/j.ebiom.2020.102904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403890/
https://www.ncbi.nlm.nih.gov/pubmed/32763828
http://dx.doi.org/10.1016/j.ebiom.2020.102904

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