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Attenuating ischemia/reperfusion injury in rat cardiac transplantation by intracoronary infusion with siRNA cocktail solution

Tumor necrosis factor-α (TNF-α), caspase-8, and complement component 5a receptor (C5aR) are known to play a crucial role in the myocardial ischemia/reperfusion (I/R) injury in cardiac transplantation. We hypothesized that the intracoronary infusion of TNF-α, caspase-8, and C5aR small interfering RNA...

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Detalles Bibliográficos
Autores principales: Yang, Bo, Wang, Jin, Zhao, Yuanyuan, Duan, Wu, Dai, Chen, Han, Zhenyi, Wang, Meixi, Zhang, Bo, Wei, Lai, Chen, Zhishui, Chen, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7403945/
https://www.ncbi.nlm.nih.gov/pubmed/32686827
http://dx.doi.org/10.1042/BSR20193937