Role of Tyr-39 for the Structural Features of α-Synuclein and for the Interaction with a Strong Modulator of Its Amyloid Assembly

Recent studies suggest that Tyr-39 might play a critical role for both the normal function and the pathological dysfunction of α-synuclein (αS), an intrinsically disordered protein involved in Parkinson’s disease. We perform here a comparative analysis between the structural features of human αS and...

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Detalles Bibliográficos
Autores principales: Palomino-Hernandez, Oscar, Buratti, Fiamma A., Sacco, Pamela S., Rossetti, Giulia, Carloni, Paolo, Fernandez, Claudio O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404028/
https://www.ncbi.nlm.nih.gov/pubmed/32709107
http://dx.doi.org/10.3390/ijms21145061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404028/
https://www.ncbi.nlm.nih.gov/pubmed/32709107
http://dx.doi.org/10.3390/ijms21145061

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