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The Role of IgG4 in the Fine Tuning of Tolerance in IgE-Mediated Allergy and Cancer

Among the four immunoglobulin G (IgG) subclasses, IgG4 is the least represented in serum of a healthy human and it is considered an “odd” antibody. The IgG4 antibody has unique structural features that affect its biological function. These include the ability to undergo antigen-binding fragment (Fab...

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Detalles Bibliográficos
Autores principales: Bianchini, Rodolfo, Karagiannis, Sophia N., Jordakieva, Galateja, Jensen-Jarolim, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404042/
https://www.ncbi.nlm.nih.gov/pubmed/32708690
http://dx.doi.org/10.3390/ijms21145017