Distal-Less Homeobox 5 Is a Therapeutic Target for Attenuating Hypertrophy and Apoptosis of Mesenchymal Progenitor Cells

Chondrocyte hypertrophy is a hallmark of osteoarthritis (OA) pathology. In the present study, we elucidated the mechanism underlying the relationship between the hypertrophy/apoptotic phenotype and OA pathogenesis in bone marrow-derived mesenchymal stem cells (BM-MSCs) via gene targeting of distal-l...

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Detalles Bibliográficos
Autores principales: Twomey-Kozak, John, Desai, Salomi, Liu, Wenguang, Li, Neill Y., Lemme, Nicholas, Chen, Qian, Owens, Brett D., Jayasuriya, Chathuraka T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404054/
https://www.ncbi.nlm.nih.gov/pubmed/32650430
http://dx.doi.org/10.3390/ijms21144823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404054/
https://www.ncbi.nlm.nih.gov/pubmed/32650430
http://dx.doi.org/10.3390/ijms21144823

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