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Distal-Less Homeobox 5 Is a Therapeutic Target for Attenuating Hypertrophy and Apoptosis of Mesenchymal Progenitor Cells
Chondrocyte hypertrophy is a hallmark of osteoarthritis (OA) pathology. In the present study, we elucidated the mechanism underlying the relationship between the hypertrophy/apoptotic phenotype and OA pathogenesis in bone marrow-derived mesenchymal stem cells (BM-MSCs) via gene targeting of distal-l...
Autores principales: | Twomey-Kozak, John, Desai, Salomi, Liu, Wenguang, Li, Neill Y., Lemme, Nicholas, Chen, Qian, Owens, Brett D., Jayasuriya, Chathuraka T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404054/ https://www.ncbi.nlm.nih.gov/pubmed/32650430 http://dx.doi.org/10.3390/ijms21144823 |
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