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Activation of NOTCH1 by Shear Force Elicits Immediate Cytokine Expression in Human Chondrocytes

Osteoarthritis is caused by overloading of joints and is characterized by inflammation-induced disruption of cartilage structure. Current treatment strategy aims to relieve inflammation and prevent further deterioration of joint function. However, how mechanical force leads to inflammation and deter...

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Detalles Bibliográficos
Autores principales: Cheng, Hao-Jen, Hsu, Wan-Ting, Chen, Cheng-Nan, Li, Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404062/
https://www.ncbi.nlm.nih.gov/pubmed/32674293
http://dx.doi.org/10.3390/ijms21144958