Downregulation of GLI3 Expression Mediates Chemotherapy Resistance in Acute Myeloid Leukemia

Aberrant activation of the hedgehog (HH) pathway is observed in many neoplasms, including acute myeloid leukemia (AML). The glioma-associated oncogene homolog (GLI) transcription factors are the main downstream effectors of the HH signaling cascade and are responsible for the proliferation and maint...

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Detalles Bibliográficos
Autores principales: Freisleben, Fabian, Behrmann, Lena, Thaden, Vanessa, Muschhammer, Jana, Bokemeyer, Carsten, Fiedler, Walter, Wellbrock, Jasmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404064/
https://www.ncbi.nlm.nih.gov/pubmed/32708452
http://dx.doi.org/10.3390/ijms21145084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404064/
https://www.ncbi.nlm.nih.gov/pubmed/32708452
http://dx.doi.org/10.3390/ijms21145084

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