Transglutaminase 2-Mediated p53 Depletion Promotes Angiogenesis by Increasing HIF-1α-p300 Binding in Renal Cell Carcinoma

Angiogenesis and the expression of vascular endothelial growth factor (VEGF) are increased in renal cell carcinoma (RCC). Transglutaminase 2 (TGase 2), which promotes angiogenesis in endothelial cells during wound healing, is upregulated in RCC. Tumor angiogenesis involves three domains: cancer cell...

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Detalles Bibliográficos
Autores principales: Lee, Seon-Hyeong, Kang, Joon Hee, Ha, Ji Sun, Lee, Jae-Seon, Oh, Su-Jin, Choi, Hyun-Jung, Song, Jaewhan, Kim, Soo-Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404067/
https://www.ncbi.nlm.nih.gov/pubmed/32708896
http://dx.doi.org/10.3390/ijms21145042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404067/
https://www.ncbi.nlm.nih.gov/pubmed/32708896
http://dx.doi.org/10.3390/ijms21145042

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