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Time-Restricted G-Protein Signaling Pathways via GPR176, G(z), and RGS16 Set the Pace of the Master Circadian Clock in the Suprachiasmatic Nucleus

G-protein-coupled receptors (GPCRs) are an important source of drug targets with diverse therapeutic applications. However, there are still more than one hundred orphan GPCRs, whose ligands and functions remain unidentified. The suprachiasmatic nucleus (SCN) is the central circadian clock of the bra...

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Detalles Bibliográficos
Autores principales: Nakagawa, Shumpei, Nguyen Pham, Khanh Tien, Shao, Xinyan, Doi, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404074/
https://www.ncbi.nlm.nih.gov/pubmed/32709014
http://dx.doi.org/10.3390/ijms21145055