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Time-Restricted G-Protein Signaling Pathways via GPR176, G(z), and RGS16 Set the Pace of the Master Circadian Clock in the Suprachiasmatic Nucleus
G-protein-coupled receptors (GPCRs) are an important source of drug targets with diverse therapeutic applications. However, there are still more than one hundred orphan GPCRs, whose ligands and functions remain unidentified. The suprachiasmatic nucleus (SCN) is the central circadian clock of the bra...
Autores principales: | Nakagawa, Shumpei, Nguyen Pham, Khanh Tien, Shao, Xinyan, Doi, Masao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404074/ https://www.ncbi.nlm.nih.gov/pubmed/32709014 http://dx.doi.org/10.3390/ijms21145055 |
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