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p62: Friend or Foe? Evidences for OncoJanus and NeuroJanus Roles
p62 is a versatile protein involved in the delicate balance between cell death and survival, which is fundamental for cell fate decision in the context of both cancer and neurodegenerative diseases. As an autophagy adaptor, p62 recognizes polyubiquitin chains and interacts with LC3, thereby targetin...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404084/ https://www.ncbi.nlm.nih.gov/pubmed/32708719 http://dx.doi.org/10.3390/ijms21145029 |