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Postsynthetic On-Column 2′ Functionalization of RNA by Convenient Versatile Method

We report a universal straightforward strategy for the chemical synthesis of modified oligoribonucleotides containing functional groups of different structures at the 2′ position of ribose. The on-column synthetic concept is based on the incorporation of two types of commercial nucleotide phosphoram...

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Detalles Bibliográficos
Autores principales: Krasheninina, Olga A., Fishman, Veniamin S., Lomzov, Alexander A., Ustinov, Alexey V., Venyaminova, Alya G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404181/
https://www.ncbi.nlm.nih.gov/pubmed/32698484
http://dx.doi.org/10.3390/ijms21145127