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Development of a Single Construct System for Site-Directed RNA Editing Using MS2-ADAR

Site-directed RNA editing (SDRE) technologies have great potential for treating genetic diseases caused by point mutations. Our group and other researchers have developed SDRE methods utilizing adenosine deaminases acting on RNA (ADARs) and guide RNAs recruiting ADARs to target RNAs bearing point mu...

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Detalles Bibliográficos
Autores principales: Tohama, Tetsuto, Sakari, Matomo, Tsukahara, Toshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404196/
https://www.ncbi.nlm.nih.gov/pubmed/32668759
http://dx.doi.org/10.3390/ijms21144943