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Resolvin D1 and D2 Inhibit Transient Receptor Potential Vanilloid 1 and Ankyrin 1 Ion Channel Activation on Sensory Neurons via Lipid Raft Modification

Transient Receptor Potential Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons and regulate nociceptor and inflammatory functions. Resolvins are endogenous lipid mediators. Resolvin D1 (RvD1) is described as a selective inhibitor of TRPA1-r...

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Detalles Bibliográficos
Autores principales: Payrits, Maja, Horváth, Ádám, Biró-Sütő, Tünde, Erostyák, János, Makkai, Géza, Sághy, Éva, Pohóczky, Krisztina, Kecskés, Angéla, Kecskés, Miklós, Szolcsányi, János, Helyes, Zsuzsanna, Szőke, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404206/
https://www.ncbi.nlm.nih.gov/pubmed/32708653
http://dx.doi.org/10.3390/ijms21145019