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Systematic Humanization of the Yeast Cytoskeleton Discerns Functionally Replaceable from Divergent Human Genes

Many gene families have been expanded by gene duplications along the human lineage, relative to ancestral opisthokonts, but the extent to which the duplicated genes function similarly is understudied. Here, we focused on structural cytoskeletal genes involved in critical cellular processes, includin...

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Detalles Bibliográficos
Autores principales: Garge, Riddhiman K., Laurent, Jon M., Kachroo, Aashiq H., Marcotte, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404242/
https://www.ncbi.nlm.nih.gov/pubmed/32522745
http://dx.doi.org/10.1534/genetics.120.303378