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Systematic Humanization of the Yeast Cytoskeleton Discerns Functionally Replaceable from Divergent Human Genes
Many gene families have been expanded by gene duplications along the human lineage, relative to ancestral opisthokonts, but the extent to which the duplicated genes function similarly is understudied. Here, we focused on structural cytoskeletal genes involved in critical cellular processes, includin...
Autores principales: | Garge, Riddhiman K., Laurent, Jon M., Kachroo, Aashiq H., Marcotte, Edward M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404242/ https://www.ncbi.nlm.nih.gov/pubmed/32522745 http://dx.doi.org/10.1534/genetics.120.303378 |
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