Immunomodulatory Effects of Hydroxychloroquine and Chloroquine in Viral Infections and Their Potential Application in Retinal Gene Therapy

Effective treatment of retinal diseases with adeno-associated virus (AAV)-mediated gene therapy is highly dependent on the proportion of successfully transduced cells. However, due to inflammatory reactions at high vector doses, adjunctive treatment may be necessary to enhance the therapeutic outcom...

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Detalles Bibliográficos
Autores principales: Chandler, Laurel C., Yusuf, Imran H., McClements, Michelle E., Barnard, Alun R., MacLaren, Robert E., Xue, Kanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404262/
https://www.ncbi.nlm.nih.gov/pubmed/32674481
http://dx.doi.org/10.3390/ijms21144972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404262/
https://www.ncbi.nlm.nih.gov/pubmed/32674481
http://dx.doi.org/10.3390/ijms21144972

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