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ADAM-Mediated Signalling Pathways in Gastrointestinal Cancer Formation

Tumour growth is not solely driven by tumour cell-intrinsic mechanisms, but also depends on paracrine signals provided by the tumour micro-environment. These signals comprise cytokines and growth factors that are synthesized as trans-membrane proteins and need to be liberated by limited proteolysis...

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Detalles Bibliográficos
Autores principales: Schumacher, Neele, Rose-John, Stefan, Schmidt-Arras, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404302/
https://www.ncbi.nlm.nih.gov/pubmed/32698506
http://dx.doi.org/10.3390/ijms21145133