Fibrocystin Is Essential to Cellular Control of Adhesion and Epithelial Morphogenesis

Mutations of the Pkhd1 gene cause autosomal recessive polycystic kidney disease (ARPKD). Pkhd1 encodes fibrocystin/polyductin (FPC), a ciliary type I membrane protein of largely unknown function, suggested to affect adhesion signaling of cells. Contributions of epithelial cell adhesion and contracti...

Descripción completa

Detalles Bibliográficos
Autores principales: Ziegler, Wolfgang H., Soetje, Birga, Marten, Lisa P., Wiese, Jana, Burute, Mithila, Haffner, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404311/
https://www.ncbi.nlm.nih.gov/pubmed/32698519
http://dx.doi.org/10.3390/ijms21145140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404311/
https://www.ncbi.nlm.nih.gov/pubmed/32698519
http://dx.doi.org/10.3390/ijms21145140

Ejemplares similares