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HLA-G Expression in Human Mesenchymal Stem Cells (MSCs) Is Related to Unique Methylation Pattern in the Proximal Promoter as well as Gene Body DNA

Multipotent human mesenchymal stem cells (MSCs) harbor clinically relevant immunomodulation, and HLA-G, a non-classical MHC class I molecule with highly restricted tissue expression, is one important molecule involved in these processes. Understanding of the natural regulatory mechanisms involved in...

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Detalles Bibliográficos
Autores principales: Yen, B. Linju, Hwa, Hsiao-Lin, Hsu, Pei-Ju, Chen, Pei-Min, Wang, Li-Tzu, Jiang, Shih-Sheng, Liu, Ko-Jiunn, Sytwu, Huey-Kang, Yen, Men-Luh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404323/
https://www.ncbi.nlm.nih.gov/pubmed/32708387
http://dx.doi.org/10.3390/ijms21145075