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NME3 Regulates Mitochondria to Reduce ROS-Mediated Genome Instability

NME3 is a member of the nucleoside diphosphate kinase (NDPK) family that binds to the mitochondrial outer membrane to stimulate mitochondrial fusion. In this study, we showed that NME3 knockdown delayed DNA repair without reducing the cellular levels of nucleotide triphosphates. Further analyses rev...

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Detalles Bibliográficos
Autores principales: Chen, Chih-Wei, Tsao, Ning, Zhang, Wei, Chang, Zee-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404397/
https://www.ncbi.nlm.nih.gov/pubmed/32708927
http://dx.doi.org/10.3390/ijms21145048