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Molecular Mechanism by Which Cobra Venom Cardiotoxins Interact with the Outer Mitochondrial Membrane

Cardiotoxin CTII from Naja oxiana cobra venom translocates to the intermembrane space (IMS) of mitochondria to disrupt the structure and function of the inner mitochondrial membrane. At low concentrations, CTII facilitates ATP-synthase activity, presumably via the formation of non-bilayer, immobiliz...

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Detalles Bibliográficos
Autores principales: Li, Feng, Shrivastava, Indira H., Hanlon, Paul, Dagda, Ruben K., Gasanoff, Edward S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404710/
https://www.ncbi.nlm.nih.gov/pubmed/32605112
http://dx.doi.org/10.3390/toxins12070425