Cargando…

Vaccination with VLPs Presenting a Linear Neutralizing Domain of S. aureus Hla Elicits Protective Immunity

The pore-forming cytotoxin α-hemolysin, or Hla, is a critical Staphylococcus aureus virulence factor that promotes infection by causing tissue damage, excessive inflammation, and lysis of both innate and adaptive immune cells, among other cellular targets. In this study, we asked whether a virus-lik...

Descripción completa

Detalles Bibliográficos
Autores principales: Joyner, Jason A., Daly, Seth M., Peabody, Julianne, Triplett, Kathleen D., Pokhrel, Srijana, Elmore, Bradley O., Adebanjo, Diane, Peabody, David S., Chackerian, Bryce, Hall, Pamela R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404987/
https://www.ncbi.nlm.nih.gov/pubmed/32664481
http://dx.doi.org/10.3390/toxins12070450